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📜 Under review

• 🍺 Charlotte Nachtegael, Jacopo De Stefani, Anothony Cnudde, Tom Lenaerts. DUVEL : An active-learning annotated biomedical corpus for the recognition of oligogenic combinations.

📜 Peer-reviewed

• ⭐ Charlotte Nachtegael, Jacopo De Stefani, Tom Lenaerts. A study of deep active learning methods to reduce labelling efforts in biomedical relation extraction, PLOS ONE, 2023; 18(12): e0292356, DOI
• Nassim Versbraegen, Barbara Gravel, Charlotte Nachtegael, Alexandre Renaux, Emma Verkinderen, Ann Nowé, Tom Lenaerts, Sofia Papadimitriou. Faster and more accurate pathogenic combination predictions with VarCoPP2.0, BMC Bioinformatics, 2023; 24: 179, DOI
• ⭐ Charlotte Nachtegael, Jacopo De Stefani, Tom Lenaerts. ALAMBIC : Active Learning Automation Methods to Battle Inefficient Curation, Proceedings of the 17th Conference of the European Chapter of the Association for Computational Linguistics: System Demonstrations, 2023; pages 117–127, DOI
• Sofia Papadimitriou, Barbara Gravel, Charlotte Nachtegael, Elfride De Baere, Bart Loeys, Miikka Vikkula, Guillaume Smits, Tom Lenaerts. Toward reporting standards for the pathogenicity of variant combinations involved in multilocus/oligogenic diseases, Human Genetics and Genomics Advances, 2023; 4: 1, 100165, ISSN 2666-2477, DOI
• ⭐ Charlotte Nachtegael and Barbara Gravel, Arnau Dillen, Guillaume Smits, Ann Nowé, Sofia Papadimitriou, Tom Lenaerts. Scaling up oligogenic diseases research with OLIDA: the Oligogenic Diseases Database, Database, 2022; Volume 2022, baac023, DOI
• Sofia Papadimitriou, Andrea Gazzo, Nassim Versbraegen, Charlotte Nachtegael, Jan Aerts, Yves Moreau, Sonia Van Dooren, Ann Nowé, Guillaume Smits, Tom Lenaerts. Predicting disease-causing variant combinations, PNAS, 2019; 116 (24): 11878-11887, DOI
• Yuichi Mishima, Laura Brueckner, Saori Takahashi, Toru Kawakami, Junji Otani, Akira Shinohara, Kohei Takeshita, Ronald Garingalao Garvilles, Mikio Watanabe, Norio Sakai, Hideyuki Takeshima, Charlotte Nachtegael, Atsuya Nishiyama, Makoto Nakanishi, Kyohei Arita, Kinichi Nakashima, Hironobu Hojo, Isao Suetake. Enhanced processivity of Dnmt1 by monoubiquitinated histone H3, Genes Cells, 2020; 25: 22-32, DOI
• 🍺 Alexandre Renaux, Sofia Papadimitriou, Nassim Versbraegen, Charlotte Nachtegael, Simon Boutry, Ann Nowé, Guillaume Smits, Tom Lenaerts. ORVAL: a novel platform for the prediction and exploration of disease-causing oligogenic variant combinations, Nucleic Acids Research, 2019; 47 (W1): W93–W98, DOI
• Nassim Versbraegen, Aziz Fouché, Charlotte Nachtegael, Sofia Papadimitriou, Andrea Gazzo, Guillaume Smits, Tom Lenaerts. Using game theory and decision decomposition to effectively discern and characterise bi-locus diseases, Artificial Intelligence in Medicine, 2019; 99: 101690, ISSN 0933-3657, DOI
• Laurence de la Kethulle de Ryhove, Eugénie Ansseau, Charlotte Nachtegael, Karlien Pieters, Céline Vanderplanck, Mieke Geens, Karen Sermon, Steve D. Wilton, Frédérique Coppée, Laurence Lagneaux, Alexandra Belayew. The Role of D4Z4-Encoded Proteins in the Osteogenic Differentiation of Mesenchymal Stromal Cells Isolated from Bone Marrow, Stem Cells and Development, 2015; 24 (22): 2674-2686, DOI